All Episodes

Displaying episodes 1 - 30 of 108 in total

Confirmation Bias and The Scientific Method I: How to Avoid Confirmation Bias

For many researchers, modern science has become about getting results rather than asking questions. Results mean publications, and publications mean more funding. Howe...

Cryo-tomography to Volume EM: Explore with Hydra Bio Plasma-FIB

Volume electron microscopy or volume EM (vEM) was named one of Nature's Technologies to Watch in 2023. The new Thermo Scientific Hydra Bio PFIB integrates advanced cry...

The 12Rs Framework: Enabling High-quality Humane Research Involving Animals

In this episode of Listen In, see how emerging and global challenges of conducting ethical animal research have led to the 12Rs Framework to guide humane experimental ...

Elevate Your Research with Spatial Insights

In this episode of Listen In, learn more about how the convergence of AI technology and scientific discovery can revolutionize our understanding of biology and disease...

Unleash New Biological Insights with Innovative Glycoanalytics

Glycosylation is a prevalent modification of proteins known to play diverse roles across a wide range of biological processes. While glycoproteins are widely recognize...

Contamination and Recovery of PFAS in Analytical Methods Requiring Filter Membranes

Liquid chromatography-mass spectrometry (LC-MS) is a crucial technique in many life sciences, including proteomics, metabolomics, pharmaceutical analysis, clinical dia...

Label-free 3D Live Cell Imaging and Quantification using Holotomography

Holotomography has emerged as a helpful tool for imaging live specimens without additional pre-treatment, such as fixation, fluorescence labeling, and excitation. It c...

Back to Buffer Basics: Everything You Need to Know About Buffers

Buffers are critical to nearly all our experiments. Poorly prepared buffers lead to failed Western blots, poor protein yields, flat binding curves—and wasted time. Und...

How to Write a Research Paper IV: Understanding the Publication Process

You have written a research paper. What now? Your research can only have an impact if someone reads it. So, you must submit your article to a journal for publication. ...

How to Write a Research Paper III: Common Problems and How to Overcome Them

The best way to solve a problem is to avoid it in the first place. While journals can and do reject articles for scientific reasons, they also reject articles for stru...

How to Write a Research Paper II: The Anatomy

All research papers have certain elements in common: Introduction, Methods, Results, and Conclusion. How can you structure your introduction to best frame the research...

How to Write a Research Paper I: Telling Your Story

Rarely do we consider writing a scientific paper as a creative exercise. But what if that could change? The best way to communicate anything is through stories. The sc...

Using Antisense to Characterize Nonsense: A Mouse Model of Progranulin-Deficient Dementia

Transgenic mouse models are important tools for testing therapeutic strategies. In this episode of Listen In, discover the benefits and essential considerations when c...

Visualizing Membrane Dynamics by Electron Microscopy

Explore how the latest electron microscopy techniques and volume imaging can capture fast, dynamic membrane and vesicle remodeling events during synaptic transmission ...

Benefits of Imaging Data in Flow Cytometry Experiments: A Panel Discussion

Experience the transformative power of unbiased, data-driven cell analysis with access to over 25 image-derived label-free parameters, empowering you to easily assess ...

Jump into 3D Organoids: Basic Culture Techniques and Advanced Applications

Organoids are three-dimensional in vitro cultures derived directly from patient tissues or induced pluripotent stem cells (iPSC) and embryonic stem cells. They self-or...

Ethical Research Practice III: Image Manipulation – What's Ok, and What's Not

As a scientific researcher, you must present your work in an unbiased, original, and representative way. Without due care and attention, it is easy to drift over the b...

Ethical Research Practice II: Reporting Negative Results and Outliers

As a scientific researcher, you must present your work in an unbiased, original, and representative way. Without due care and attention, it is easy to drift over the b...

Ethical Research Practice I: Plagiarism – What It Is and How to Avoid It

As a scientific researcher, you must present your work in an unbiased, original, and representative way. Without due care and attention, it is easy to drift over the b...

Everyday Culture Practice: Improving Reproducibility in Cell Culture

Eukaryotic cell cultures respond to the slightest influence. Apart from the risk of contamination, minimal changes in cultivation parameters can affect their viability...

Precision and Efficiency at Your Fingertips: Why Electronic Pipettes are the Future of Pipetting

Many scientists see the added value in using electronic pipettes and have already upgraded their pipette fleet. The benefits include:• Reduced strain on thumbs and arm...

Introduction to Liquid Handling for Next-generation Sequencing Workflows

Next-generation sequencing (NGS) has revolutionized the ‘omics’ era, with the rapid decoding of massive DNA sequences, supporting the investigation into various biolog...

Essentials in Centrifugation—Better Safe than Sorry!

Centrifugation is the cornerstone of lab life, used in nearly every workflow, be it a routine task like pelleting cells or a dedicated assay for an important biomolecu...

Ten Common Statistical Mistakes to Watch out for When Writing or Reviewing a Manuscript

Some scientific papers are unbelievable as they showcase experimental excellence that we did not think possible. These papers astound us with their groundbreaking find...

How to Keep Your ULT Freezer Healthy

Your ultra-low temperature (ULT) freezer is not just a storage room for samples; it is your assurance for long-term scientific success and guards the results of your w...

Reproducibility: Mastering the Art of Pipetting

Have you ever transferred glycerol or ethanol with a pipette? We all know how hard it is, and we've all been dubious about the accuracy of our final volumes. While you...

Real-time IntraVital Microscopy (IVM): In Vivo Cellular-level Imaging of Internal Organs in a Live Animal

Intravital imaging of cellular dynamics in a natural physiological microenvironment can provide unprecedented insights into the dynamic pathophysiology of diseases. In...

Errors and Misconduct in Biomedical Research

What are the motives behind science misconduct? How is data manipulated to evidence dubious results? And do you think you can spot edited and faked data? Any fraud in ...

Garbage In, Garbage Out: Sample Prep for Flow Cytometry

What's more disappointing than running your flow cytometry sample to discover it's rubbish? Especially considering time on cytometers can be precious, even more so if ...

Consistent, Error-Free Writing: Tips and Tricks for Time-starved Scientists

Scientific writing is an art that requires as much attention and proficiency as your hands-on lab work. When done right, it can significantly contribute to your scient...