Inspired by mutations associated with neurodevelopmental disorders, Prof. Dr. Silvia Cappello’s group at the Ludwig Maximilian University of Munich aims to understand the role of extracellular mechanisms essential for the correct development of the human brain.

Their research focuses on intrinsic and extrinsic mechanisms contributing to the formation of the brain by examining mutations in genes influencing cell-cell contacts, the extracellular matrix, and the secretion of vesicles.

In this episode of Listen In, Silvia presents the latest research that makes an important contribution to our understanding of cell non-autonomous mechanisms in the development of neurodevelopmental disorders.

She also explains how imaging workflows, using the Mica Imaging Microhub alongside confocal and super-resolution systems, support the group’s research.

Watch the full presentation here: https://microscopyfocus.com/cellular-crosstalk-in-neurodevelopmental-disorders/

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