Precise, high-efficiency editing of stem cells to probe human biology and model disease

Discover how combining two nobel-prize winning technologies—cell reprogramming and CRISPR gene editing—creates a powerful platform to study basic cell biology, development, and disease. You'll learn how this technology overcomes problems with more traditional immortalized cell models and see how it is already being used to study neurodegenerative diseases.

This webinar is presented by Bill Skarnes, Professor of Cellular Engineering at The Jackson Laboratory.

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Creators and Guests

Bill Skarnes Ph.D.
Guest
Bill Skarnes Ph.D.
Bill received his B.Sc. and M.Sc. in Microbiology and Immunology from McGill University in Montreal, Canada. In 1992, he was awarded his Ph.D. in Molecular and Medical Genetics from the University of Toronto, where he pioneered gene-trapping technology in mouse embryonic stem cells. In 1997, Bill took up an appointment as an Assistant Professor at the University of California at Berkeley. From 2003 to 2016, Bill led the Mouse Developmental Genetics and embryonic stem Cell Mutagenesis teams at the Welcome Trust Sanger Institute in the United Kingdom, focusing on the generation of a genome-wide collection of conditional knockouts in mouse. He has over 80 peer review publications and is now based at The Jackson Laboratory for Genomic Medicine in Farmington, Connecticut, as the Director of Cellular Engineering. Bill's laboratory is currently exploiting new genome-editing technology to study gene function and model disease in human stem cells.
Precise, high-efficiency editing of stem cells to probe human biology and model disease